ISO files and Daemon Tools

Have a couple of game ISO’s (AOE 2, The Settlers, and some others) on my hard disk which I mount and installed with Daemon Tools. They install fine but when I try to run them from Daemon Tools .... get messages like “cannot run the CD” or “please insert the correct CD-ROM, select OK and restart application” .. etc. which still do not work. Tried enabling emulation like Safedisc, RMPS, Securom, etc based on what I’ve researched on the web, but still don’t work. What am i doing wrong ? Do I HAVE TO burn the ISO’s to CD in order to play the games ? Any help would be appreciated.

im having the same exact problem i think we might have to put the iso. file onto a blank CD to run it but im hoping someone will tell me a way to run it from my hardrive so im gunna wait a bit before i burn the CD.